Anju, A and Joseph, Jeswin and Thomas, P C and Paulton, M P and Vijayan, K K (2015) Messenger RNA expression of pattern recognition receptor proteins in the pearl oyster Pinctada fucata (Gould, 1850) in response to lipopolysaccharide stimulation. Indian Journal of Fisheries, 62 (3). pp. 151-156. ISSN 0970 - 6011
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Abstract
Pattern recognition receptor proteins (PRP) are capable of binding specifically to conserved portion of microbial cell wall components and they are involved in the recognition of different immune modulators. Proteins such as F-type lectin, galectin and LGBP play protective role in innate immunity of invertebrates. The time dependent expression of F-type lectin gene as well as galectin and LGBP genes was determined after lipopolysaccharide (LPS) challenge in the pearl oyster Pinctada fucata. A significant increase of mRNA expression levels of all the three genes under study was observed in haemocytes, reaching a maximum level at 8 h post-challenge and then declined to basal levels at 36 h. These results suggest that PRPs play a critical role in the innate immune system of the pearl oyster P. fucata.
| Item Type: | Article |
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| Uncontrolled Keywords: | Lipopolysaccharide, mRNA expression, Pattern recognition receptor proteins, Pinctada fucata, Semi-quantitative PCR |
| Subjects: | Molluscan Fisheries > Pearl oyster Fish Genetics |
| Divisions: | CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division Subject Area > CMFRI > CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division Subject Area > CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division |
| Depositing User: | Arun Surendran |
| Date Deposited: | 21 Oct 2015 11:07 |
| Last Modified: | 22 Oct 2015 04:44 |
| URI: | http://eprints.cmfri.org.in/id/eprint/10531 |
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