Sequential development of histopathological manifestations in response to experimental infection of Vibrio alginolyticus in Asian Seabass

Azhar Shahansha, T S and Pradeep, M A and Sharma, S R Krupesha and Sreenath, K R and Suja, G and Joshy, Aswathy and Sanil, N K (2024) Sequential development of histopathological manifestations in response to experimental infection of Vibrio alginolyticus in Asian Seabass. Journal of the Marine Biological Association of India, 66 (1). pp. 9-14. ISSN 2321-7898

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Abstract

Asian seabass (Lates calcarifer), an important species for mariculture in the Asia-Pacific region, has been threatened by various infectious diseases hampering the profitability of its aquaculture. Vibriosis is the most common disease leading to considerable mortality and economic loss. Recent studies revealed that Vibrio alginolyticus is one of the most common species that causes vibriosis in farmed aquatic animals, including L. calcarifer. Despite our understanding of the aetiology, there is little information on the subsequent histological changes following experimental infection in fish. The present study fills this gap by investigating the sequential histopathological alterations in Asian seabass post intraperitoneal injection with V. alginolyticus. Significant organ changes were seen in the spleen, kidneys, liver, and to a lesser extent, the gills. The findings revealed an initial latency before major tissue responses occurred, with the kidney exhibiting the earliest and most severe changes. The spleen and liver also showed substantial alterations, while the gills showed minor changes. Experimental V. alginolyticus infection resulted in 90-95% mortality within 24-48 hours post-challenge. Our findings contribute to a more thorough understanding of histological changes in Asian seabass during V. alginolyticus infection, highlighting the importance of disease progression, and mitigation measures.

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