Marine macroalga‑associated heterotrophic Bacillus velezensis: a novel antimicrobial agent with siderophore mode of action against drug‑resistant nosocomial pathogens

Vinaya, K K and Chakraborty, Kajal (2021) Marine macroalga‑associated heterotrophic Bacillus velezensis: a novel antimicrobial agent with siderophore mode of action against drug‑resistant nosocomial pathogens. Journal of Aquatic Food Product Technology. pp. 1-14.

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Abstract

Increased prevalence of microbial resistance and development of drug-resistant pathogens have triggered an urge among researchers to discover potential antimicrobial compounds, particularly from the marine habitat. The present study highlights the cultivable diversity and bioactivities of heterotrophic bacteria associated with marine macroalgae of southeast Indian coastal region. Culture-dependent isolation method resulted in 40 isolates, in which greater part of the isolates represented Gammaproteobacteria (62%) followed by that comprised of the phylum Firmicutes. One of the most active strains isolated from a macroalga, Laurencia papillosa, was characterized based on the integrated phenotypic and genotypic analysis as Bacillus velezensis MBTDLP1 MTCC 13048, with an inhibition zone of about 35 mm against methicillin-resistant Staphylococcus aureus (MRSA), was selected for bioprospecting studies.

Item Type:	Article
Subjects:	Biochemistry Algae
Divisions:	CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division Subject Area > CMFRI > CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division Subject Area > CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division
Depositing User:	Mr. Prashanth P K
Date Deposited:	18 Sep 2021 07:20
Last Modified:	16 Mar 2023 06:26
URI:	http://eprints.cmfri.org.in/id/eprint/15277

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