Lipton, A P and Sunith, Shine (2009) Mariculture of marine sponges for drug development : bioactivity potentials of cultured sponges, Callyspongia subarmigera (Ridley) and Echinodictyum gorgonoides (Dendy). Marine Fisheries Information Service T&E Series (202). pp. 7-10.
Among all metazoan phyla, marine sponges are considered as the richest source of biologically and pharmacologically active chemicals. More than 5,300 different products are recorded from sponges and their associated microorganisms. Every year, about 200 new metabolites are reported from sponges. Considering the emerging diseases and the rapid development of disease resistance among microbes, the detection of novel metabolites from sponges gains importance and also provides scope for developing new drugs against disease causing bacteria, virus, fungi and parasites. In nature, the chemical interactions in the marine habitat of sponges suggest that products from them function as defense tools to protect them against predators including fish. Sponge product ara-A (vidarabine), the anti-viral drug used against the Herpes simplex encephalitis virus has advanced to the late stages of clinical trials.
|Uncontrolled Keywords:||Mariculture; marine sponges; drug development; bioactivity potentials; cultured sponges; Callyspongia subarmigera; Echinodictyum gorgonoides|
|Subjects:||Aquaculture > Mariculture
Marine Ecosystems > Sponges
Marine Ecosystems > Gorgonids
|Divisions:||CMFRI-Cochin > Mariculture|
|Depositing User:||Geetha P Mrs|
|Date Deposited:||18 Nov 2010 09:10|
|Last Modified:||09 Sep 2015 15:38|
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