Mariculture of marine sponges for drug development : bioactivity potentials of cultured sponges, Callyspongia subarmigera (Ridley) and Echinodictyum gorgonoides (Dendy)

Lipton, A P and Sunith, Shine (2009) Mariculture of marine sponges for drug development : bioactivity potentials of cultured sponges, Callyspongia subarmigera (Ridley) and Echinodictyum gorgonoides (Dendy). Marine Fisheries Information Service T&E Series (202). pp. 7-10.

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Abstract

Among all metazoan phyla, marine sponges are considered as the richest source of biologically and pharmacologically active chemicals. More than 5,300 different products are recorded from sponges and their associated microorganisms. Every year, about 200 new metabolites are reported from sponges. Considering the emerging diseases and the rapid development of disease resistance among microbes, the detection of novel metabolites from sponges gains importance and also provides scope for developing new drugs against disease causing bacteria, virus, fungi and parasites. In nature, the chemical interactions in the marine habitat of sponges suggest that products from them function as defense tools to protect them against predators including fish. Sponge product ara-A (vidarabine), the anti-viral drug used against the Herpes simplex encephalitis virus has advanced to the late stages of clinical trials.

Item Type:Article
Uncontrolled Keywords:Mariculture; marine sponges; drug development; bioactivity potentials; cultured sponges; Callyspongia subarmigera; Echinodictyum gorgonoides
Subjects:Aquaculture > Mariculture
Marine Ecosystems > Sponges
Marine Ecosystems > Gorgonids
Divisions:CMFRI-Cochin > Mariculture
ID Code:6469
Deposited By:Geetha P Mrs
Deposited On:18 Nov 2010 14:40
Last Modified:18 Nov 2010 14:40

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