Electron microscopy in disease diagnosis - Winter school on recent advances in diagnosis and management of diseases in mariculture, 7th to 27th November 2002, Course Manual

Abstract

Understanding the pathogen and the pathogenesis at cellular levels are imperative in the studies of disease causing organisms. With its very high resolving and magnifying powers. Electron Microscopy has opened up new vistas in studying the ultra structure and has become an indispensable tool in understanding many of the diseases and their etiological agents. Transmission electron microscopy (TEM) can reveal the ultra structural details at cellular levels, whereas Scanning electron microscopy (SEM) can A show the morphology of minute structures/organisms in three-dimensional state. Combining the TEM and SEM, it has become possible to study and classify the viruses and virus like organisms.