Electron microscopy in disease diagnosis In: Winter School on Vistas in Marine Biotechnology 5th to 26th October 2010

Sanil, N K and Vijayan, K K (2010) Electron microscopy in disease diagnosis In: Winter School on Vistas in Marine Biotechnology 5th to 26th October 2010. [Teaching Resource]

Text Vistas in Marine Biotechnology_2010_Chp 41.pdf Download (28kB)

Abstract

Understanding the pathogen and the pathogenesis at cellular levels are imperative in the studies of disease causing organisms. With its very high resolving and magnifying powers, Electron Microscopy has opened up new vistas in studying the ultra structure and has become an indispensable tool in understanding many of the diseases and their etiological agents. The limitations of Light Microscopes, low magnifying and resolving powers (1000 x magnification and a resolution of 0.2 micrometers) paved the way for the development of electron microscopes. Electron Microscopes are instruments that use a beam of highly energetic electrons to examine objects on a very fine scale and function exactly like their optical counterparts. Present day electron microscopes are capable of giving magnifications up to 1000000 X and 800000 X and a resolving power of 0.1 nm and 0.4 nm in T E M and S E M respectively. Transmission electron microscopy (TEM) can reveal the ultra structural details at cellular levels, whereas Scanning electron microscopy (SEM) can show the morphology of minute structures/organisms in its three-dimensional state. Combining the TEM and SEM, it has become possible to study and classify the viruses and virus like organisms.

Item Type:	Teaching Resource
Uncontrolled Keywords:	Microscopy; disease; diagnosis
Subjects:	Fish Biotechnology Fish Diseases
Divisions:	CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division Subject Area > CMFRI > CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division Subject Area > CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division
Depositing User:	Arun Surendran
Date Deposited:	09 Feb 2023 11:35
Last Modified:	09 Feb 2023 11:35
URI:	http://eprints.cmfri.org.in/id/eprint/16714

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