Mosquito Larvicidal Activity of Marine Sponge Metabolites

Annie Selva Sonia, G and Lipton, A P (2012) Mosquito Larvicidal Activity of Marine Sponge Metabolites. Global Journal of Pharmacology, 6 (1). pp. 1-3.

Global Journal of Pharmacology_2012_Lipton A P.pdf

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    The secondary metabolites of five species of marine sponge viz., Acanthella elongata, Echinodictyum gorgonoides, Axinella donnani, Callyspongia subarmigera and Callyspongia diffusa collected off Kanyakumari were explored for vector control activity. The extracts were assayed against larvae of Culex sp, the mosquito vector of filariasis as per the World Health Organization protocols. The test doses varied from 0.01% to 10.0% for 24h from which LC were determined. Maximum mosquito larvicidal activity 50 was noted in the methanol extract of Acanthella elongata with the LC50 of 0.066 mg/ml. Axinella donnani was the least active among the tested sponges. The results of present investigation suggest that A. elongata extract has the potential for developing novel bioactive larvicidal agent.

    Item Type: Article
    Uncontrolled Keywords: Sponge metabolites; Mosquito; larvicidal activity; Culex sp
    Subjects: Marine Ecosystems > Sponges
    Divisions: CMFRI-Vizhinjam
    Depositing User: Arun Surendran
    Date Deposited: 31 Mar 2021 11:30
    Last Modified: 31 Mar 2021 11:30

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