Pharmacological properties of some mangrove sediment-associated bacillus isolates

Rajan, Lakshmi and Chakraborty, Kajal and Chakraborty, Rekha D (2021) Pharmacological properties of some mangrove sediment-associated bacillus isolates. Archives of Microbiology, 203. pp. 67-76.

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Abstract

Mangrove sediment-associated bacteria are of significantly important in the field of medicine and pharmaceuticals as new promising sources of biologically active pharmacophores due to the extreme conditions, such as high salt concentration and soil anoxia. The sediment bacteria associated with Acanthus ilicifolius and Avicennia officinalis collected from the Mangalavanam mangrove ecosystem of the Kerala State of India were evaluated using various in vitro models for the assessment of their pharmacological properties. The bacteria exhibiting significant antioxidant and antimicrobial activities were isolated, identified, and characterized by the integrated microbiological, biochemical, and 16S rRNA sequencing. Among the varied bacteria isolated from mangrove sediments, Bacillus amyloliquefaciens MBMS5 (GenBank accession number MK765025) exhibited significant antimicrobial activities against various pathogenic bacteria, such as Aeromonas caviae, Vibrio parahemolyticus, and methicillin-resistant Staphylococcus aureus. The extracellular extracts of B. amyloliquefaciens MBMS5 exhibited potential antioxidant activity against free radical species coupled with anti-inflammatory property as displayed by the attenuation activity against pro-inflammatory 5-lipoxygenase.

Item Type:	Article
Uncontrolled Keywords:	Mangrove sediment-associated bacteria; Bacillus amyloliquefaciens MBMS5; Pharmacological properties; Antimicrobial; Antioxidant and anti-inflammatory activities
Subjects:	Algae > Bacteria Biochemistry > Bioactive compounds Biochemistry
Divisions:	CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division Subject Area > CMFRI > CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division Subject Area > CMFRI-Kochi > Marine Biotechnology, Fish Nutrition and Health Division CMFRI-Kochi > Marine Capture > Crustacean Fisheries Division Subject Area > CMFRI > CMFRI-Kochi > Marine Capture > Crustacean Fisheries Division CMFRI-Kochi > Marine Capture > Crustacean Fisheries Division Subject Area > CMFRI-Kochi > Marine Capture > Crustacean Fisheries Division
Depositing User:	Arun Surendran
Date Deposited:	02 Feb 2021 05:06
Last Modified:	02 Feb 2021 05:06
URI:	http://eprints.cmfri.org.in/id/eprint/14825

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