Sulphated galactopyran derived from Gracilaria opuntia, a marine macroalgae restores the antioxidant metabolic enzymes during STZ induced diabetic rats

Lavanya, R and Makkar, Fasina and Anusree, M and Chakraborty, Kajal and Valluru, Lokanatha (2017) Sulphated galactopyran derived from Gracilaria opuntia, a marine macroalgae restores the antioxidant metabolic enzymes during STZ induced diabetic rats. Journal of Coastal Life Medicine, 5 (2). pp. 59-65.

[img] Text
Journal of Coastal Life Medicine_galactopyran from Gracilaria_2017_Kajal Chakraborty.pdf
Restricted to Registered users only

Download (860kB) | Request a copy
Official URL: http://oaji.net/articles/2017/2154-1485309660.pdf
Related URLs:

    Abstract

    In vitro antioxidant assays of FM4 were estimated by DPPH, ABTS, hydroxyl free radical and Nitric oxide free radical activities. FM4 was purified and characterized by 1H-NMR spectra and FTIR as sulphated galactopyran. Diabetes was induced intraperitonially by single dose of STZ (55 mg/kg body weight). FM4 was administrated orally (80, 100, 125 mg/kg BW) to diabetic rats for 60 days. The enzymatic and non-enzymatic antioxidants such as superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), glutathione-S-transferase (GST), lipid peroxidase (LPx), glutathione reduced (GSH), vitamin-C (VIT-C) and vitamin-E (VIT-E) levels were estimated. Glibenclamide was used as standard drug.

    Item Type: Article
    Uncontrolled Keywords: Marine macroalgae Oxidative stress Antioxidants Streptozotocin Diabetes
    Subjects: Biochemistry > Bioactive compounds
    Algae
    Divisions: CMFRI-Kochi > Marine Biotechnology
    Subject Area > CMFRI > CMFRI-Kochi > Marine Biotechnology
    CMFRI-Kochi > Marine Biotechnology
    Subject Area > CMFRI-Kochi > Marine Biotechnology
    Depositing User: Arun Surendran
    Date Deposited: 13 Feb 2017 07:11
    Last Modified: 13 Feb 2017 07:11
    URI: http://eprints.cmfri.org.in/id/eprint/11538

    Actions (login required)

    View Item View Item