Messenger RNA expression of pattern recognition receptor proteins in the pearl oyster Pinctada fucata (Gould, 1850) in response to lipopolysaccharide stimulation

Anju, A and Joseph, Jeswin and Thomas, P C and Paulton, M P and Vijayan, K K (2015) Messenger RNA expression of pattern recognition receptor proteins in the pearl oyster Pinctada fucata (Gould, 1850) in response to lipopolysaccharide stimulation. Indian Journal of Fisheries, 62 (3). pp. 151-156. ISSN 0970 - 6011

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    Abstract

    Pattern recognition receptor proteins (PRP) are capable of binding specifically to conserved portion of microbial cell wall components and they are involved in the recognition of different immune modulators. Proteins such as F-type lectin, galectin and LGBP play protective role in innate immunity of invertebrates. The time dependent expression of F-type lectin gene as well as galectin and LGBP genes was determined after lipopolysaccharide (LPS) challenge in the pearl oyster Pinctada fucata. A significant increase of mRNA expression levels of all the three genes under study was observed in haemocytes, reaching a maximum level at 8 h post-challenge and then declined to basal levels at 36 h. These results suggest that PRPs play a critical role in the innate immune system of the pearl oyster P. fucata.

    Item Type: Article
    Uncontrolled Keywords: Lipopolysaccharide, mRNA expression, Pattern recognition receptor proteins, Pinctada fucata, Semi-quantitative PCR
    Subjects: Molluscan Fisheries > Pearl oyster
    Fish Genetics
    Divisions: CMFRI-Kochi > Marine Biotechnology
    Subject Area > CMFRI > CMFRI-Kochi > Marine Biotechnology
    CMFRI-Kochi > Marine Biotechnology
    Subject Area > CMFRI-Kochi > Marine Biotechnology
    Depositing User: Arun Surendran
    Date Deposited: 21 Oct 2015 11:07
    Last Modified: 22 Oct 2015 04:44
    URI: http://eprints.cmfri.org.in/id/eprint/10531

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