Simple and reliable assay to detect immunosuppresant activity in Macroalge

Lipton, A P and Pramitha, V S (2014) Simple and reliable assay to detect immunosuppresant activity in Macroalge. International Journal of Pharmaceutical, Chemical and Biological Sciences, 4 (1). pp. 139-144.

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    Abstract

    The possible immunosuppressant activity of extracts of Ulva fasciata, Hypnea valentiae and Hypnea musciformis was evaluated by fish scale transplantation assay. The crude Hypnea extracts exhibited delayed acceptance of transplanted scale from 4th day onwards in the F2 progeny of Poecilia reticulata at 0.001% level compared to fractionated extract of Ulva fasciata. No rejection of transplanted scale was noticed at 0.01% of Ethanol-fresh extract of U. fasciata (EF) fraction up to 10th day of experiment. Rejection of transplanted scale was noticed in the case of acetone and ethanol - fresh extract among the F2 progeny from 3rd and 4th day respectively.

    Item Type: Article
    Uncontrolled Keywords: Ulva fasciata; Poecilia reticulata; Hypnea valentiae; Hypnea musciformis
    Subjects: Algae
    Divisions: CMFRI-Vizhinjam
    Depositing User: Arun Surendran
    Date Deposited: 29 Jul 2014 04:54
    Last Modified: 09 Sep 2015 15:59
    URI: http://eprints.cmfri.org.in/id/eprint/10148

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